Lentiviral Vectors and Gene Therapy - David Escors,Karine Breckpot,Frederick Arce - cover
Lentiviral Vectors and Gene Therapy - David Escors,Karine Breckpot,Frederick Arce - cover
Dati e Statistiche
Salvato in 0 liste dei desideri
Lentiviral Vectors and Gene Therapy
Disponibilità in 2 settimane
68,70 €
68,70 €
Disp. in 2 settimane

Descrizione


Gene therapy was conceived during the early and mid part of the 20th century. At first, it was considered a revolutionary biomedical procedure, which could potentially cure any disease for which the molecular bases were understood. Since then, gene therapy has gone through many stages and has evolved from a nearly unrealistic perspective to a real life application. Clinical efficacy in humans was demonstrated at the beginning of this century after its successful application in small-scale clinical trials to cure severe immunodeficiency in children. However, their successes were overshadowed some time later by the occurrence of vector-related leukaemia in a number of treated children. It is in this context that lentiviral vectors have appeared, with improved efficiency and, possibly, increased biosafety. Very recently, the first clinical trials with lentivectors have been carried out with some success. This Brief firstly defines gene therapy, and places lentivectors within this fascinating therapeutic strategy. Then follows a comprehensive description of the development of retroviral and lentiviral vectors and how to specifically target distinct cell types and tissues. The authors also discuss the application of lentivector gene therapy for the treatment of cancer and autoimmune diseases, ending with the application of lentivectors in human gene therapy clinical trials.

Dettagli

104 p.
Testo in English
235 x 155 mm
9783034804011
Informazioni e Contatti sulla Sicurezza dei Prodotti

Le schede prodotto sono aggiornate in conformità al Regolamento UE 988/2023. Laddove ci fossero taluni dati non disponibili per ragioni indipendenti da Feltrinelli, vi informiamo che stiamo compiendo ogni ragionevole sforzo per inserirli. Vi invitiamo a controllare periodicamente il sito www.lafeltrinelli.it per eventuali novità e aggiornamenti.
Per le vendite di prodotti da terze parti, ciascun venditore si assume la piena e diretta responsabilità per la commercializzazione del prodotto e per la sua conformità al Regolamento UE 988/2023, nonché alle normative nazionali ed europee vigenti.

Per informazioni sulla sicurezza dei prodotti, contattare productsafety@feltrinelli.it