Brain Metallomics

This volume explores the diverse roles that metals play in the brain, including their distribution, regulatory mechanisms, and involvement in disease. The chapters focus on methods to measure neurometals with various technologies and discuss the latest advancements in the field ranging from the molecular underpinnings of metal ion homeostasis and detection to the latest research on how metal dysregulation can lead to brain pathologies. Each chapter covers specific aspects of metal biology in the brain and offers practical insights into the sophisticated methods used to study metal distribution and function. Each chapter also discusses potential therapeutic approaches to modulate metal homeostasis in disease and provides a roadmap for future research and clinical practice. In the Neuromethods series style, chapters include the kind of detail and key advice from the specialists needed to get successful results in your laboratory. Comprehensive and authoritative, Brain Metallomics is a valuable resource for both novice and expert researchers, clinicians, and students in the field. This book will inspire further research and discussion on the critical roles that metals play in the brain, fostering a sense of community amongst its readers.