The Ontology of Physics for Biology: Semantic Modeling of Multiscale, Multidomain Physiological Systems

Offers an overview dealing with semantic models of large-scale physiological systems, from qualitative and quantitative representation to computing. Shows how to implement computational techniques for building a comprehensive semantic toolbox. Demonstrates how modern bio-ontologies are used to develop and improve small- and large-scale simulation models, with examples given from the domains of diabetes and metabolism, and cardiovascular function. Covers the underlying concepts and best practices for ontology design. Gives in-depth discussion of domain and application ontologies, class definitions, object relations, and reasoning.