Advances in Structural Biology: Applications in Protein Structure, Function, and Disease

Advances in Structural Biology: From Protein Structures to Function and Disease offers a comprehensive, practical resource that bridges the latest experimental and computational approaches in structural biology. Backed by real-world case studies, the book demonstrates how these technologies can be utilized to serve a range of biological needs. The content spans foundational principles of protein structure and bioinformatics tools, cutting-edge methodologies such as MicroED and Cryo-EM, and the transformative role of artificial intelligence and big data analytics in structural biology. It also considers applications including drug discovery, vaccine development, antiviral therapy, personalized medicine, and the structural basis of aging and neurodegenerative diseases. Readers will find detailed investigation into the latest developments in structural and computational biology, including insights into integrative methodologies that combine both traditional and emerging technologies. This resource is invaluable for advanced students, researchers, and professionals aiming to harness structural biology for innovative solutions in precision medicine and translational research.